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For research and pharmaceutical organizations only. No consumer sales.

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Oligonucleotides

Research-grade oligos to clinical GMP supply.

Antisense, siRNA and other therapeutic oligonucleotides with a full range of backbone and sugar modifications, conjugation chemistry, and a development path to GMP.

Quality and documentation
01

Research-Grade Synthesis

Antisense (ASO)

Gapmers and steric-blocking ASOs.

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siRNA Duplexes

Annealed duplexes with sense and antisense QC.

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miRNA, PMO & Aptamers

miRNA mimics and inhibitors, morpholinos, aptamers.

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CpG & Decoy Oligos

Immunostimulatory CpG and transcription-factor decoys.

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02

Chemistry & Conjugates

Backbone & Sugar Modifications

Phosphorothioate, 2'-OMe, 2'-F, 2'-MOE, LNA.

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Labels & Dyes

Fluorescent, quencher and biotin labeling.

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GalNAc Conjugates

Liver-targeted tri-antennary GalNAc conjugation.

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Peptide & Lipid Conjugates

POCs, PPMOs and lipid conjugates for delivery.

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03

Development & Manufacturing

Oligo NCE / CMC Development

Route scouting, analytics and regulatory support.

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Clinical & Commercial GMP

GMP drug substance from clinical batches upward.

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Quality & Regulatory

GMP-aligned quality systems, change control and regulatory documentation for filings.

Analytical Capabilities

HPLC, LC-MS, NMR, amino acid analysis and residual solvent testing in-house.

Documentation

Certificate of analysis with every lot, plus method and stability data on request.

Ready to scope your oligonucleotides project?

Share your sequence, structure or specification and our technical team will reply with a quotation.

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